AMPHOTERICIN-B should be administered intravenously under supervision of the doctor. Fever chills, nausea, vomiting, anorexia, headache, arthralgia and hypotension are common when AMPHOTERICIN-B
is given.
Liver function, renal function, serum electrolytes (particularly magnesium and potassium) and blood count should be monitored frequently during AMPHOTERICIN-B therapy.
Under no circumstances a total daily dose should not exceed 1.5 mg/kg. The duration of treatment may be 6 to 12 weeks or longer.